Vocabulary What does お手数 (おてすう, otesuu) mean? お手数 (おてすう, otesuu) means trouble; bother. Quick factsReadingおてすうRomajiotesuuPart of speechnoun お手数おてすうotesuutrouble; bother1noun trouble; botherAlso written: 御手数Kanji in this word手hand数number, quantity; count